I-Innovation in Oral Thin Film Drugs:Ukuletha Imithi Yakusasa

Umhlaba wezokwelapha uhlala ushintsha njengoba sithola izindlela ezintsha zokwelapha izifo. Enye yentuthuko yakamuva ekulethweni kwezidakamizwa yi-ngomlomo mncane-ifilimuumuthi. Kodwa yini imithi yefilimu yomlomo, futhi isebenza kanjani?

Imithi yefilimu yomlomo imithi ehanjiswa ngefilimu encane, ecacile ehlakazeka ngokushesha lapho ibekwe olimini noma ngaphakathi esihlathini. Enziwe ngama-polymers ancibilikayo emanzini aphephile ukuthi angadliwa, lawa mafilimu angenziwa ngendlela oyifisayo ukuze alethe izinhlobo ezahlukene zezidakamizwa.

Enye yezinzuzo eziningi zemithi yefilimu yomlomo ukuthi kulula ukuyisebenzisa, ikakhulukazi kubantu abanenkinga yokugwinya amaphilisi noma amaphilisi. Futhi zihlakaniphile futhi azidingi ukukha amanzi, okuzenza zilungele abantu abamatasa noma labo abangakwazi ukuhamba.

Imithi yomlomo enefilimu elincanyana iye yaletha ngempumelelo izinhlobonhlobo zezidakamizwa, okuhlanganisa ukudambisa izinhlungu, imithi yokulwa nokungezwani komzimba nezinto ezithile, ngisho namavithamini. Zisetshenziselwa futhi ukuphatha ukuncika kwe-opioid kanye nemithi yezimo zempilo yengqondo.

Inzuzo enkulu yengomlomo mncane-ifilimuukulethwa kwezidakamizwa yikhono lokwenza umthamo wezidakamizwa uhambisane nezidingo zesiguli ngasinye, okuwenza uphumelele futhi unciphise ingozi yemiphumela engemihle. Ubuchwepheshe buvumela futhi ukulethwa kwezidakamizwa okunembe kakhudlwana, ukuqinisekisa ukuphathwa kwezidakamizwa okungaguquki nempumelelo.

Nokho, njenganoma yibuphi ubuchwepheshe obusha,ngomlomo mncane-ifilimuukulethwa kwezidakamizwa kuletha izinselele ezithile. Isithiyo esisodwa inqubo yokugunyaza yokulawula, edinga ukuhlolwa nokuhlolwa okubanzi ukuze kuqinisekiswe ukuthi iphephile futhi iyasebenza.

Naphezu kwalezi zinselelo,ngomlomo mncane-ifilimuukulethwa kwezidakamizwa kusalokhu kuwuhlelo olusha oluthembisayo kubuchwepheshe bokulethwa kwezidakamizwa. Inamandla okuguqula indlela esithatha ngayo imithi futhi ithuthukise izimpilo zabantu abaningi emhlabeni jikelele.

Kafushane, izidakamizwa zomlomo zefilimu elincanyana zimelela ukuthuthukiswa okukhulu kubuchwepheshe bokulethwa kwezidakamizwa, ngezinzuzo ezifana nokusebenziseka kalula, ukulinganisa okunembile, kanye nemithi yomuntu siqu. Yize kusenezinselelo okufanele sizinqobe, singalindela ukuthi lokhu kuqanjwa kabusha kube nomthelela omuhle ekwenzeni imithi ifinyeleleke kuwo wonke umuntu.